Matthew A. J. Duncton : rechercher sur Z-Library

David R. Adams, Matthew A. J. Duncton

Année:

1999

Fichier:

PDF, 24 KB

1999

ChemInform Abstract: Efficient Synthesis of the 5-HT2C Receptor Agonist, Org 37684.

Journal:

David R. Adams, Matthew A. J. Duncton, Jonathan R. A. Roffey, John Spencer

Année:

2001

Fichier:

PDF, 35 KB

2001

Preparation of 6-Chloro-5-fluoroindole via the Use of Palladium- and Copper-Mediated Heterocyclizations.

Journal:

Steven M. Allin, Christopher I. Thomas, James E. Allard, Matthew Duncton, Mark R. J. Elsegood, Mark Edgar

Année:

2003

Fichier:

PDF, 143 KB

2003

Stereoselective Synthesis of the Indolizinoindole Ring System.

Journal:

Evgueni L. Piatnitski, Matthew A. J. Duncton, Alexander S. Kiselyov, Reeti Katoch-Rouse, Dan Sherman, Daniel L. Miligan, Chris Balagtas, Wai C. Wong, Joel Kawakami, Jacqueline F. Doody

Année:

2003

Fichier:

PDF, 23 KB

2003

Arylphthalazines: Identification of a New Phthalazine Chemotype as Inhibitors of VEGFR Kinase.

Journal:

Matthew A. J. Duncton, M. Angels Estiarte, Russell J. Johnson, Matthew Cox, Donogh J. R. O'Mahony, William T. Edwards, Michael G. Kelly

Année:

2006

Fichier:

PDF, 19 KB

2006

ChemInform Abstract: Preparation of Heteroaryloxetanes and Heteroarylazetidines by Use of a Minisci Reaction.

Journal:

Kiran P. Sahasrabudhe, M. Angels Estiarte, Darlene Tan, Sheila Zipfel, Matthew Cox, Donogh J. R. O'Mahony, William T. Edwards, Matthew A. J. Duncton

Année:

2010

Fichier:

PDF, 29 KB

2010

ChemInform Abstract: A Single-Step Preparation of Thiazolo[5,4-b]pyridine- and Thiazolo[5,4-]pyridine Derivatives from Chloronitropyridines and Thioamides, or Thioureas.

Journal:

Année:

2010

Fichier:

PDF, 30 KB

2010

ChemInform Abstract: Minisci Reactions: Versatile C—H Functionalizations for Medicinal Chemists

Matthew A. J. Duncton

Journal:

Kiran P. Sahasrabudhe, M. Angels Estiarte, Darlene Tan, Sheila Zipfel, Matthew Cox, Donogh J. R. O'Mahony, William T. Edwards, Matthew A. J. Duncton

Année:

2012

Fichier:

PDF, 11 KB

2012

A single-step preparation of thiazolo[5,4-b]pyridine- and thiazolo[5,4-c]pyridine derivatives from chloronitropyridines and thioamides, or thioureas

Journal:

Journal of Heterocyclic Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 109 KB

english, 2009

Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase

Leon Smith II, Wai C. Wong, Alexander S. Kiselyov, Sabina Burdzovic-Wizemann, Yunyu Mao, Yongjiang Xu, Matthew A.J. Duncton, Ki Kim, Evgueni L. Piatnitski, Jacqueline F. Doody, Ying Wang, Robin L. Ros

Journal:

Matthew A.J. Duncton, Eugene L. Piatnitski Chekler, Reeti Katoch-Rouse, Dan Sherman, Wai C. Wong, Leon M. Smith II, Joel K. Kawakami, Alexander S. Kiselyov, Daniel L. Milligan, Chris Balagtas, Yaron R

Année:

2006

Langue:

english

Fichier:

PDF, 137 KB

english, 2006

Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2

Journal:

Bioorganic & Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 304 KB

english, 2009

Arylphthalazines. Part 2: 1-(Isoquinolin-5-yl)-4-arylamino phthalazines as potent inhibitors of VEGF receptors I and II

Matthew A.J. Duncton, Evgueni L. Piatnitski, Reeti Katoch-Rouse, Leon M. Smith II, Alexander S. Kiselyov, Daniel L. Milligan, Chris Balagtas, Wai C. Wong, Joel Kawakami, Jacqueline F. Doody

Journal:

Fabien Vincent, Margaret T. Nguyen, Daniel E. Emerling, Michael G. Kelly, Matthew A.J. Duncton

Année:

2006

Langue:

english

Fichier:

PDF, 105 KB

english, 2006

Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): Identification of phenmedipham and amperozide as FAAH inhibitors

Journal:

Jeff DeFalco, Daniel Steiger, Amy Gustafson, Daniel E. Emerling, Michael G. Kelly, Matthew A.J. Duncton

Année:

2009

Langue:

english

Fichier:

PDF, 637 KB

english, 2009

Oxime derivatives related to AP18: Agonists and antagonists of the TRPA1 receptor

Journal:

Jeff DeFalco, Daniel Steiger, Michelle Dourado, Daniel Emerling, Matthew A.J. Duncton

Année:

2010

Langue:

english

Fichier:

PDF, 410 KB

english, 2010

5-Benzyloxytryptamine as an antagonist of TRPM8

Journal:

Matthew A.J. Duncton, Jonathan R.A. Roffey, Richard J. Hamlyn, David R. Adams

Année:

2010

Langue:

english

Fichier:

PDF, 421 KB

english, 2010

Parallel synthesis of N-arylpiperazines using polymer-assisted reactions

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 106 KB

english, 2006

Synthesis of unsymmetrical and regio-defined 2,3,6-quinoxaline and 2,3,7-pyridopyrazine derivatives

Dan Sherman, Joel Kawakami, Hai-Ying He, Farah Dhun, Raphael Rios, Hu Liu, Weitao Pan, Yong-Jiang Xu, Sang-phyo Hong, Melissa Arbour, Marc Labelle, Matthew A.J. Duncton

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 129 KB

english, 2007

Dibutyl 2-(trifluoromethyl)cyclopropylboronate as a useful (trifluoromethyl)cyclopropyl donor: application to antagonists of TRPV1

Matthew A.J. Duncton, Leticia Ayala, Carl Kaub, Satyanarayana Janagani, William T. Edwards, Nina Orike, Krithika Ramamoorthy, John Kincaid, Michael G. Kelly

Journal:

David R. Adams, Matthew A.J. Duncton, Jonathan R.A. Roffey, John Spencer

Année:

2010

Langue:

english

Fichier:

PDF, 477 KB

english, 2010

Preparation of 6-chloro-5-fluoroindole via the use of palladium and copper-mediated heterocyclisations

Journal:

Steven M. Allin, Christopher I. Thomas, James E. Allard, Matthew Duncton, Mark R.J. Elsegood, Mark Edgar

Année:

2002

Langue:

english

Fichier:

PDF, 178 KB

english, 2002

Stereoselective synthesis of the indolizinoindole ring system

Journal:

Evgueni L. Piatnitski, Matthew A.J. Duncton, Alexander S. Kiselyov, Reeti Katoch-Rouse, Dan Sherman, Daniel L. Milligan, Chris Balagtas, Wai C. Wong, Joel Kawakami, Jacqueline F. Doody

Année:

2003

Langue:

english

Fichier:

PDF, 140 KB

english, 2003

Arylphthalazines: Identification of a new phthalazine chemotype as inhibitors of VEGFR kinase

Journal:

Vincent, Fabien, A.J. Duncton, Matthew

Année:

2005

Langue:

english

Fichier:

PDF, 101 KB

english, 2005

Minisci reactions: Versatile CH-functionalizations for medicinal chemists

Duncton, Matthew A. J.

Journal:

MedChemComm

Année:

2011

Langue:

english

Fichier:

PDF, 623 KB

english, 2011

TRPV4 Agonists and Antagonists

Journal:

Current Topics in Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 196 KB

english, 2011

Preparation of Substituted Pyrimido[4,5-b]-1,4-benzoxazepines, Thiazepines, and Diazepines via a Pictet−Spengler Cyclization

Duncton, Matthew A. J., Smith, Leon M., Burdzovic-Wizeman, Sabina, Burns, Aaron, Liu, Hu, Mao, Yunyu, Wong, Wai C., Kiselyov, Alexander S.

Journal:

Biochemical and Biophysical Research Communications

Année:

2005

Langue:

english

Fichier:

PDF, 116 KB

english, 2005

Preparation of Aryloxetanes and Arylazetidines by Use of an Alkyl−Aryl Suzuki Coupling

Duncton, Matthew A. J., Estiarte, M. Angels, Tan, Darlene, Kaub, Carl, O’Mahony, Donogh J. R., Johnson, Russell J., Cox, Matthew, Edwards, William T., Wan, Min, Kincaid, John

Journal:

Organic Letters

Année:

2008

Langue:

english

Fichier:

PDF, 393 KB

english, 2008

Identification and characterization of novel TRPV4 modulators

Fabien Vincent, Alejandra Acevedo, Margaret T. Nguyen, Michelle Dourado, Jeff DeFalco, Amy Gustafson, Peter Spiro, Daniel E. Emerling, Michael G. Kelly, Matthew A.J. Duncton

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 365 KB

english, 2009

Efficient Preparation of ((3‐Chloro‐2‐fluoro‐phenyl)‐[7‐methoxy‐8‐(3‐morpholin‐4‐yl‐propoxy)‐10,11‐dihydro‐5‐oxa‐2,4,11‐triaza‐dibenzo(a,d)cyclohepten‐1‐yl]‐amine) for In‐Vivo Study

Liu, Hu, Smith, Leon M., Mao, Yunyu, Pan, Weitao, Xu, Yong‐Jiang, Burdzovic‐Wizeman, Sabina, Duncton, Matthew A. J., Wong, Wai C.

Journal:

Synthetic Communications

Année:

2006

Langue:

english

Fichier:

PDF, 108 KB

english, 2006

A concise one-pot synthesis of trifluoromethyl-containing 2,6-disubstituted 5,6,7,8-tetrahydroquinolines and 5,6,7,8-tetrahydronaphthyridines

Johnson, Russell J., O'Mahony, Donogh J. R., Edwards, William T., Duncton, Matthew A. J.

Journal:

Bentley, Jon M., Davidson, James E., Duncton, Matthew A. J., Giles, Paul R., Pratt, Robert M.

Année:

2013

Langue:

english

Fichier:

PDF, 256 KB

english, 2013

Use of a Modified Leimgruber–Batcho Reaction to Prepare 6‐Chloro‐5‐fluoroindole

Journal:

Synthetic Communications

Année:

2004

Langue:

english

Fichier:

PDF, 134 KB

english, 2004

4-Substituted-3-phenylquinolin-2(1 H )-ones: Acidic and Nonacidic Glycine Site N -Methyl- d -aspartate Antagonists with in Vivo Activity

Carling, Robert W., Leeson, Paul D., Moore, Kevin W., Moyes, Christopher R., Duncton, Matthew, Hudson, Martin L., Baker, Raymond, Foster, Alan C., Grimwood, Sarah, Kemp, John A., Marshall, George R.,

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 434 KB

english, 1997

EFFICIENT SYNTHESIS OF THE 5-HT 2C RECEPTOR AGONIST, ORG 37684

Adams, David R., Duncton, Matthew A. J.

Journal:

Synthetic Communications

Année:

2001

Langue:

english

Fichier:

PDF, 177 KB

english, 2001

Synthesis of trans -2-(Trifluoromethyl)cyclopropanes via Suzuki Reactions with an N -Methyliminodiacetic Acid Boronate

Duncton, Matthew A. J., Singh, Rajinder

Journal:

Organic Letters

Année:

2013

Langue:

english

Fichier:

PDF, 476 KB

english, 2013

Preparation of Heteroaryloxetanes and Heteroarylazetidines by Use of a Minisci Reaction

Duncton, Matthew A. J., Estiarte, M. Angels, Johnson, Russell J., Cox, Matthew, O’Mahony, Donogh J. R., Edwards, William T., Kelly, Michael G.

Journal:

Katritzky, Alan R., Mohapatra, Prabhu P., Fedoseyenko, Dmytro, Duncton, Matthew, Steel, Peter J.

Année:

2009

Langue:

english

Fichier:

PDF, 820 KB

english, 2009

1-Benzotriazol-1-yl-3,3,3-trifluoro-2-methoxy-2- phenylpropan-1-ones: Mosher-Bt Reagents

Journal:

DeFalco, Jeff, A.J. Duncton, Matthew, Emerling, Daniel

Année:

2007

Langue:

english

Fichier:

PDF, 83 KB

english, 2007

Discovery of potent, non-carbonyl inhibitors of fatty acid amide hydrolase (FAAH)

Gowlugari, Sumithra, DeFalco, Jeff, Nguyen, Margaret T., Kaub, Carl, Chi, Candace, Duncton, Matthew A. J., Emerling, Daniel E., Kelly, Michael G., Kincaid, John, Vincent, Fabien

Journal:

MedChemComm

Année:

2012

Langue:

english

Fichier:

PDF, 528 KB

english, 2012

TRP Channels as Therapeutic Targets || Small Molecule Agonists and Antagonists of TRPV4

Duncton, Matthew A.J.

Année:

2015

Langue:

english

Fichier:

PDF, 367 KB

english, 2015

TRPM8 Biology and Medicinal Chemistry

Journal:

Current Topics in Medicinal Chemistry

Année:

2011

Fichier:

PDF, 238 KB

2011

TRPM8 Biology and Medicinal Chemistry

DeFalco, Jeff, A.J. Duncton, Matthew, Emerling, Daniel

Journal:

Current Topics in Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 238 KB

english, 2011

ChemInform Abstract: Synthesis of trans-2-(Trifluoromethyl)cyclopropanes via Suzuki Reactions with an N-Methyliminodiacetic Acid Boronate.

Duncton, Matthew A. J., Singh, Rajinder

Journal:

Johnson, Russell J., O'Mahony, Donogh J. R., Edwards, William T., Duncton, Matthew A. J.

Année:

2014

Fichier:

PDF, 32 KB

2014

ChemInform Abstract: A Concise One-Pot Synthesis of Trifluoromethyl-Containing 2,6-Disubstituted 5,6,7,8-Tetrahydroquinolines and 5,6,7,8-Tetrahydronaphthyridines.

Journal:

Duncton, Matthew A. J., Singh, Rajinder

Année:

2013

Fichier:

PDF, 22 KB

2013

A one-pot synthesis of tetrazolones from acid chlorides: understanding functional group compatibility, and application to the late-stage functionalization of marketed drugs

Journal:

Duncton, Matthew A. J., Murray, Ryan B., Park, Gary, Singh, Rajinder

Année:

2016

Langue:

english

Fichier:

PDF, 310 KB

english, 2016

Tetrazolone as an acid bioisostere: application to marketed drugs containing a carboxylic acid

Journal:

Zhang, Jing, Kolluri, Rao, Alvarez, Salvador G., Irving, Mark M., Singh, Rajinder, Duncton, Matthew A. J.

Année:

2016

Langue:

english

Fichier:

PDF, 252 KB

english, 2016

Enantioselective synthesis of an octahydroindolizine (indolizidine) alcohol using an enzymatic resolution

Journal:

Gordon, Eric M., Duncton, Matthew A. J., Gallop, Mark

Année:

2017

Langue:

english

Fichier:

PDF, 336 KB

english, 2017

Orally Absorbed Derivatives of the β-Lactamase Inhibitor Avibactam. Design of Novel Prodrugs of Sulfate Containing Drugs.

Journal:

Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 347 KB

english, 2018

Synthesis of 9-Nitro-5-spiro[benzo[]tetrazolo[1,5-][1,4] oxazepine-4,2’-oxirane] an Unusual Ring-Expansion

Kolluri, Rao, Zhang, Jing, Singh, Rajinder, Duncton, Matthew A.J.

Journal:

O'Mahony, Donogh J.R., Johnson, Russell J., Estiarte, M. Angels, Edwards, William T., Duncton, Matthew A.J.

Année:

2018

Langue:

english

Fichier:

PDF, 455 KB

english, 2018

A practical asymmetric synthesis of ortho-substituted 4-pyrazolyl-2-ethylamines

Journal:

Wang, Brian J, Duncton, Matthew A. J.

Année:

2019

Langue:

english

Fichier:

PDF, 499 KB

english, 2019

A Single-Step Synthesis of Azetidine-3-amines

Journal: